Cellular 'alchemy' transforms skin into blood
Direct conversion of cell types could offer safer, simpler treatments than stem cells.
Human skin cells can be transformed into blood without first being sent through a primordial, stem-cell-like state, according to a ground-breaking study
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Haemophiliac left out in the cold
Mark Metherell HEALTH CORRESPONDENT
Haemophilia patients with hepatitis C have won government payments of tens of thousands of dollars each in New Zealand, Britain and Canada.
05 November 2010A "huge" variation exists in the amounts of coumarin in bark samples of cassia cinnamon from trees growing in Indonesia, scientists are reporting in a new study. That natural ingredient in the spice may carry a theoretical...
Polymorphism Associated with Good Antiviral Response but Also Depression in HCV Nov 4
Growth Factor Drugs Bolster Compliance in Hepatitis C Therapy Nov 3
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Belly Fat: 3 Tips on How to Lose It Visceral fat is dangerous for a variety of reasons:
It has a direct route to the liver and can negatively increase liver function tests such as cholesterol.
It is linked with dumping inflammatory hormones into your body, which can affect your heart, kidney and brain.
It is associated with insulin resistance, which is an inability of your body to respond appropriately to your own insulin, which in turn increases fat storage and blood sugars.
It is connected with increased rates of cancer and cancer-like growths in the body.
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Regenerating body parts lost by soldiers who have been injured in war is the topic of our story from McGowan Institute for Regenerative Medicine at the University of Pittsburgh. “Powder Regenerates New Muscle” covers the encouraging results of an experimental procedure using a biologic compound made from harvested pig bladder. Watch to see how the experimental powder, when placed near a wound, actually signals the human body to begin generating new cells and has already been effective for regenerating the human esophagus, in addition to muscle regeneration.
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Studying the metabolome of smokers, Lombardi researchers find early signs of damage Our analysis uncovered hallmarks of liver, heart, and kidney toxicity in otherwise healthy patients," says the study's lead investigator, Ping-Ching Hsu, a doctoral student who works in the laboratory of oncology researcher Peter Shields, MD, who specializes in tobacco carcinogenesis. Shields is the senior author.
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"Breakthrough in Cancer Vaccine Research Researchers hope to revolutionize cancer therapy after discovering one of the reasons why many previous attempts to harness the immune system to treat cancerous tumors have ... > full story
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Genetic Testing for Hepatitis C Virus Genotype 2 or 3 Infection IL28B genotype was an independent predictor of sustained virologic response to HCV therapy.
Polymorphisms in the IL28B gene have been shown to play an important role in how patients infected with hepatitis C virus (HCV) genotype 1 develop chronic infection and respond to treatment (JW Gastroenterol Oct 16 2009). Now, researchers have evaluated the potential role of IL28B polymorphisms in patients infected with HCV genotype 2 or 3.
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Combining telaprevir regimen with standard therapy improves SVR rate in hepatitisC November 2010 00:15 For patients with the most common form of hepatitis C being treated for the first time, the addition of an investigational hepatitis C-specific protease inhibitor called telaprevir to the current standard therapy markedly improved their sustained viral response (SVR or viral cure) rate. [More]
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Aaron knows only too well how important it is that people volunteer to donate their organs if they die – even children.
Ten years ago, he received a combined liver and small bowel transplant at Birmingham Children’s Hospital. His donor was another child
Diabetes patient gets gift of life from a stranger "Imagine what it feels like to walk around having done that for a total stranger," Segal said of his donor. "I’m in awe of it every day, and I can’t say enough. I get up in the morning and I look in the mirror and I say … ‘I’m here again. I wasn’t supposed to be here.’ "
Addictive drugs like valium (diazepam) may also shrink your brain Once regarded as wonder drugs against anxiety, depression and other undesirable mental states, these medicines are under scrutiny now that a 30- year-old, leaked study shows that risks and dangers were known early on, yet the drugs were prescribed anyway...
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31. Safety and Antiviral Activity of ANA598 in Combination with Pegylated Interferon α2A Plus Ribavirin in Treatment-Naïve Genotype-1 Chronic HCV Patients
81. High rates of early viral response, promising safety profile and lack of resistance-related breakthrough in HCV GT 1/4 patients treated with RG7128 plus PegIFN alfa-2a (40KD)/RBV: Planned Week 12 interim analysis from the PROPEL study.
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Updates November 4th
1855. Initial antiviral activity of the HCV NS3 protease inhibitor ABT-450 when given with low dose ritonavir as 3-day monotherapy: Preliminary results of study M11-602 in genotype-1 (GT1) HCV-infected treatment-naïve subjects. (Updated November 4, 2010)
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