Thursday, May 10, 2018

Listen: The struggle to study hepatitis C virus with Charlie Rice

Host: Julie Wolf
Charlie Rice gives the history of learning to grow hepatitis C virus in culture, from pitfalls to hurdles and successes along the 20-year journey. He also talks about yellow fever virus, its vaccine, and the importance of curiosity-driven research.

One of the interesting properties of Hepatitis C as compared to some of the other flaviviruses like yellow fever virus for example is that it is extremely good at establishing and maintaining a chronic infection in most people who are infected. So if you progress to this chronic stage, which occurs in about 60-70% of those that become infected, you’re stuck with the virus for life unless you’re successfully treated.”

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