Saturday, September 8, 2018

Risk of Liver Cancer in Patients with NAFLD

Severe NAFLD Boosts Liver Cancer Risk
By Ankur Banerjee

(Reuters Health) - People with advanced cases of nonalcoholic fatty liver disease (NAFLD) may need to be monitored for liver cancer, a large U.S. study suggests.

Fatty liver disease is known to be linked with a higher risk of hepatocellular carcinoma (HCC). But it hasn't been clear whether some patients are more at risk than others.

The new study showed that when NAFLD progresses to cirrhosis, the risk for HCC is dramatically higher.

The findings suggest that people with NAFLD and cirrhosis should be monitored for HCC, the authors wrote in Gastroenterology, online August 23.

Risk of HCC was higher in NAFLD patients than that observed in general clinical population. Most HCC cases in NAFLD developed in patients with cirrhosis. The absolute risk of HCC was higher than the accepted thresholds for HCC surveillance for most patients with NAFLD cirrhosis.

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