Direct-Acting Antivirals Effective for Hepatitis C in Seniors

Wednesday, June 27, 2018

Direct-Acting Antivirals Effective for Hepatitis C in Seniors

MONDAY, June 25, 2018 -- For older patients with hepatitis C virus (HCV), direct-acting antiviral (DAA) therapy is effective, according to a study published online May 25 in the Journal of the American Geriatrics Society.

Chiara Mazzarelli, M.D., from King's College Hospital in London, and colleagues conducted a retrospective review involving individuals aged 65 years and older treated with DAA therapy for HCV. Participants were divided into two cohorts: 88 aged 65 to 74 years and 25 aged 75 years and older.

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Direct-acting antivirals reduce risk of premature mortality and liver cancer for people with chronic hepatitis C

These findings firmly counter those of a Cochrane review of direct-acting antiviral treatment trials that could neither confirm nor reject if direct-acting antivirals had an effect on long-term HCV-related morbidity and mortality. They also provide the best evidence to date to support guidance documents that recommend direct-acting antiviral treatment for all patients with chronic HCV infection.

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Wednesday, June 27, 2018