Monday, March 4, 2013

Meal consumption confounds liver stiffness measurements in patients with chronic HCV



Meal consumption confounds liver stiffness measurements in patients with chronic HCV

Arena U. Hepatology. 2013;doi:10.1002/hep.26343.

March 4, 2013
Liver stiffness varied significantly during a 2-hour period after consumption of a meal, and it impaired detection of fibrosis and esophageal varices in patients with chronic hepatitis C in a recent study.
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Initial results suggest efficacy of simeprevir/sofosbuvir in prior null-responders with HCV

March 4, 2013
Medivir AB recently announced interim results from a phase IIa study of a regimen of simeprevir and sofosbuvir in patients with hepatitis C who had been non-responsive to prior interferon-based therapy.
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Early ART may achieve ‘functional cure’ in children with HIV

March 4, 2013
Early application of antiretroviral therapy may prevent establishment of a latent reservoir and achieve cure in HIV-positive children, according to results of a case report presented at the 2013 Annual CROI Meeting in Atlanta.

Researchers from Johns Hopkins Children’s Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School presented a novel case of a “functional HIV cure” in a 26-month-old infected child who commenced ART at 30 hours of age.
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