Study shows link between hepatitis C and prostate cancer
A retrospective database study of all men who underwent transrectal ultrasound guided prostate biopsy over 3 years was conducted by members of Lincoln Medical and Mental Health Center, Department of Urology, Bronx, NY and New York Medical College, Valhalla, NY. The men were 49% African or African Caribbean, and 51% Central or South American. Information in the database included prostate specific antigen (PSA), cholesterol, hepatitis A, B and C, human immunodeficiency virus (HIV), syphilis, tuberculin skin testing and histology data.
The database was created of all men who underwent transrectal prostate biopsy at Lincoln Medical and Mental Health Center fromJanuary 1, 2007, through December 31, 2009. Compiled data results revealed a correlation between hepatitis C antibody detection and prostate cancer.
Whether there is a direct connection between the hepatitis C virus and prostate cancer cannot be determined at this present time. The database was created of all men who underwent transrectal prostate biopsy at Lincoln Medical and Mental Health Center fromJanuary 1, 2007, through December 31, 2009. Compiled data results revealed a correlation between hepatitis C antibody detection and prostate cancer.
However, men 40 and over, especially those who have been treated for hepatitis C, will want to have a PSA screening to rule out the possibility of prostate cancer. Bronx residents interested in obtaining a free PSA screening can receive one up to June 26, 2011 at participating hospitals as part of a public health initiative sponsored by the New York Daily News.
http://www.examiner.com/prostate-cancer-in-new-york/study-shows-link-between-hepatitis-c-and-prostate-cancer
Certainly both of them are strongly correlated.
ReplyDeletePresently I am running an investigation about Literature Based Discovery (LBD) in which I am proposing that several Prostate disases could be ameliorated with Nitazoxanide. One of the B-terms that links these two biomedical literatures (Nitazoxanide and Prostate cancer) delivered by the Arrowsmith tool while retrieving data to discover my hypothesis was precisely "hepatitis C virus".
Just take a look at mi blog in this same site and see what I mean (sorry,in spanish).
I found the next three papers that can help you to confirm that correlation:
1) Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-lenght hepatitis C virus
RNA. 2011
2) Hepatitis C virus in elderly cancer patients, 2006
3) Association between inmune thrombocytopenic purpura and chronic lymphocytic leukemia in a patient carrier of anti-hepatitis C virus antibodies. 2005
If you are not familiar with Arrowsmith tool, you can retrieve these papers from PubMed.