Friday, February 2, 2018

February 2018 Hepatitis Updates: Opioid Addiction, Newsletters & Can HCV Reactivate with Treatment of Non-hepatic Cancer

February 2018 Hepatitis Updates
Greetings, here is a recap of today's news, along with this months index of wonderful newsletters, publications, and blog updates; offering us invaluable information on the topic of viral hepatitis.

News Updates
MD Magazine
HCV Can Reactivate with Treatment of Non-hepatic Cancer
Hepatitis C virus (HCV) reactivation to occur in approximately 1 out of 5 patients treated for non-hepatic cancer, posing renewed risk for hepatic injury and possibly complicating the cancer treatment....

Here is the study, published last month in Hepatology “Hepatitis C virus reactivation in patients receiving cancer treatment: A prospective observational study

FEBRUARY 02, 2018
Kenneth Bender, PharmD, MA
A growing number of children are being hospitalized with hepatitis C virus (HCV) infection, coinciding with the increase in substance abuse in the US and the disproportionately greater rates in the northeast and southern regions.

Reuters Health
Hep B reactivation common during direct-acting antiviral therapy for hep C
Last Updated: 2018-02-02
By Will Boggs MD
NEW YORK (Reuters Health) - Hepatitis B virus (HBV) reactivation is common in patients with chronic HBV and hepatitis C virus (HCV) coinfection receiving direct-acting antiviral (DAA) therapy, according to a systematic review and meta-analysis.

"It is important to identify patients at risk of HBV reactivation," said Dr. Johannes Vermehren from University Hospital Frankfurt, in Frankfurt am Main, Germany.

"HBsAg-positive patients who also have detectable HBV DNA should be closely monitored when treated for hepatitis C with direct antivirals. Alternatively, (nucleoside/nucleotide) prophylaxis may be justified in these patients," he told Reuters Health by email.

Read today's news or a nice summary of notable headlines published in the latest issue of The Weekly Bull.

William F. Balistreri
February 01, 2018
Although several studies have examined the frequency of various causes of abnormal liver test results in the general population and the role of liver biopsy in diagnosis, to date no controlled trials have been performed to determine the optimal approach to evaluating patients.

8 recent reports on prevention, prediction of cirrhosis
February 2, 2018
Chronic liver damage known as cirrhosis has a variety of causes. What remains constant is its potential progression to liver failure. Researchers continue to seek…
View all headlines @ Healio

Healio - In the Journals
SVR for HCV with no advanced liver disease greatly reduces mortality risk
Backus LI, et al. Hepatol. 2017;doi:10.1016/j.cgh.2017.07.032.
January 30, 2018
Patients with hepatitis C without advanced liver disease who achieved sustained virologic response with direct-acting antiviral therapy had significantly reduced all-cause mortality rates compared with both treated patients who did not achieve SVR and untreated patients, according to a recently published data.

World Hepatitis Alliance
Over the past two decades, deaths caused by liver cancer have increased by 80% , making it one of the fastest-growing causes of cancer deaths worldwide. According to the Global Burden of Disease Study, the most comprehensive worldwide observational epidemiological study to date, 830,000 people died as a result of the disease in 2016 compared to 464,000 people in 1990. This makes liver cancer the second leading cause of cancer deaths worldwide, after lung cancer.

How to Find a Cancer Doctor
Feb 4, 2018
Cancer changes your life and the lives of those around you. Finding the right cancer doctor (called an oncologist) and treatment facility is an important step to getting the treatment and support you need.

The International Agency for Research on Cancer (IARC) is the specialized cancer agency of the World Health Organization
World Cancer Day is 4 February.
Cancer kills 8.8 million people every year, and it's on the rise. Learn more about the European Code Against Cancer and 12 ways to reduce your cancer risk.

GI & Hepatology News
Baby boomers are the hepatitis C generation
Richard Franki Frontline Medical News
Publish date: February 2, 2018
Adults born before and after the boomers have much lower rates of hepatitis C–related hospitalizations.

infohep news
Harm reduction scale-up needed to eliminate HCV in people who inject drugs, European model predicts
Keith Alcorn / 01 February 2018
Elimination of hepatitis C among people who inject drugs in Europe will require simultaneous scale-up of direct-acting antiviral treatment, needle and syringe programmes (NSP) and opioid substitution treatment (OST)

Understanding The Struggle Against Opioid Addiction
NPR's Rachel Martin talks to Medicaid's former Chief Medical Officer Andrey Ostrovsky about his uncle's fatal drug overdose and his efforts to destigmatize opioid addiction.

NAM Publications
A new edition of our booklet HIV stigma & discrimination' is now available online. The booklet explains what stigma and discrimination are, makes some suggestions for how to deal with these problems and gives information about your legal rights. 
The purpose of this Training Manual is to provide information for you and your community. This information can be used to advocate for access to prevention and diagnosis of, and care and treatment for, hepatitis C virus (HCV).

The manual is written by and for people who are not medical specialists. We're treatment activists who learned about HCV because it was a problem for people in our communities.

The primary goals of the Training Manual are to increase advocates’ knowledge about available HCV tests and treatments, particularly in the era of all-oral, highly effective direct-acting antiviral medications that treat all genotypes, and to jumpstart discussions on advocacy strategies that can be used to open up affordable access for more people with HCV.

We designed it to help you understand basic information about HCV and coinfection with HIV: how it's transmitted, how to prevent HCV, how people can find out if they have HCV, what happens to both HIV-negative and HIV-positive people who have HCV, testing and treatment options, drug-drug interactions, and other information used for making treatment decisions.

This Training Manual is organized into short sections, and each section can be presented and shared by a trainer or peer educator with a small group of people in one to two hours. There are discussion points and action steps at the end of each section. The discussion points are intended to start conversations about the key issues raised in each section. The action steps are intended to start conversations about how to translate the key issues into advocacy in the community and to allow participants to find solutions together.

In Case You Missed It - Journal Updates
Original Article: Glecaprevir–Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection
Full Text Article: Shared and downloaded via Twitter by Henry E. Chang 
View all Journal updates on this blog, here.....

HCV Advocate
February Newsletter
Hepatitis A (HAV) Overview
HealthWise – Love, Sex, and Hepatitis C

Recommended reading at HCV Advocate
A Guide to Understanding and Managing Fatigue – learn about how fatigue can affect the body and mind and how to manage it.
A Guide for Employers and Coworkers – Living with hepatitis C is not easy. This fact sheet is designed to help you to educate employers and co-workers, but it’s a tricky business at the very least. But disclosure could prove to be helpful for the person living with HCV.
Meditation – most of us live stressful lives. Living with HCV can be even very stressful. This fact sheet offers helpful tips on various meditation techniques.
Sleep – Everyone needs it and it is an important component of living well with hepatitis C.

National Viral Hepatitis Roundtable
NVHR Newsletter

Save The Date - February 6, 2018
National Viral Hepatitis Roundtable NVHR
Engaging Active Drug Users About Hep C: From Testing Through Cure and Beyond
Tuesday, February 6, 2018, 12 pm Pacific/3 pm Eastern
Click here to register

Are drug users informing your agency’s programs and policies?
Do you know how to engage drug users?
What can be done to address concerns about adherence to hepatitis C treatment by people who use drugs?

We’ll discuss these questions and more during a webinar on February 6, 2018. The webinar will be hosted by the National Viral Hepatitis Roundtable, the Urban Survivor’s Union, the People’s Harm Reduction Alliance, and the Atlanta Harm Reduction Coalition. These groups are working collaboratively on the “More than Tested, Cured” project which addresses barriers to hepatitis C care faced by individuals who use drugs. The webinar will also include findings from interviews with participants and healthcare providers and suggested messaging to improve access to hepatitis C care. After the presentation, there will be time for questions and discussion.

The New York City Hepatitis C Task Force
Hep Free NYC Newsletters

British Liver Trust

Blog Updates
By Editorial Team - February 1, 2018
How do you tell your friends and family or romantic partners you’ve been diagnosed with hepatitis C? Just the stigma of hepatitis C alone can make relationships challenging enough. Add in symptoms...

By Kimberly Morgan Bossley - February 1, 2018
Ever go to your appointment and feel like your doctor is speaking a different language? Many times, going in to see my liver doctor I would be sitting there waiting with a list...

By Daryl Luster - January 30, 2018
Lost to care is a phrase that is not commonly mentioned in the community or really anywhere else very much. What does it mean? In the context of hep C, it relates...

HEP Blog
January 31, 2018
By Connie M. Welch
The preparation phase for treatment is very important. Knowledge is powerful. When patients prepare they are more likely to be proactive and handle treatment much easier.

By Lucinda K. Porter, RN
If your hepatitis was cured, but a new doctor tells you that you have hep C, should you panic? A look at what may be going on.

By Lucinda K. Porter, RN
Hepatitis C reactivation may occur in people receiving cancer treatment. However, hep C reactivation may not mean what you think it does.

By Karen Hoyt
A glimpse at an easily overlooked tool for healing.

The Hepatitis B Foundation
Herbal Remedies and Supplements
Herbal remedies are not regulated or tested for efficacy, safety or purity. At best they are supportive, but sometimes they cause more harm than good.

Harvard Health Blog
Posted February 02, 2018, 6:30 am
Are we headed toward a historically bad flu season? It’s too early to tell. This year, it could just be that flu season, which is usually at its worst in February, is peaking early. Hospitals across the United States have been flooded with flu patients. Matters have been made worse by national shortages of IV fluids in the wake of Hurricane Maria.

FDA Statement - Impact of saline shortages during this flu season
February 02, 2018
Statement from FDA Commissioner Scott Gottlieb, MD, on ongoing efforts to mitigate impact of saline shortages during this flu season
This year’s flu season has been particularly challenging, with a notable number of cases leading to hospitalization. The season started earlier than usual and seemed to spread across many states quickly. H3N2, the predominant strain of the influenza A virus this season, has led to health complications that are more severe than those seen during an H1N1-predominant season. We recognize that managing the thousands of flu-related hospitalizations has increased the demand for certain saline products – which are commonly used to both hydrate and deliver medications via intravenous routes. As we’ve shared over the past several months, across the country, there remains a shortage of IV saline bags, which have long faced supply issues. These supply issues were worsened by the impact of Hurricane Maria on the medical products manufacturing sector in Puerto Rico, which impacted small volume IV bags. Although the saline shortage is improving, this year’s worse-than-normal flu season and workarounds deployed by health care providers in the wake of this shortage have increased demand for saline and other products.

This flu season's hospitalizations are highest in nearly a decade
by Lena H. Sun February 2 at 2:17 PM
This year's flu season has now sent more people to the hospital with the illness than in nearly a decade, federal health officials said Friday. Nationwide during the past week, 16 more children died from the virus.

So far this season, influenza has caused the deaths of at least 53 children, rivaling that of the especially severe 2014-2015 flu season. Eighty percent of them had not had a flu shot....

Enjoy the upcoming weekend!

Photo Credit: Bygone Boys

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