Sunday, December 31, 2017

Women receive more inpatient resections and ablations for hepatocellular carcinoma than men

World J Hepatol. Dec 28, 2017; 9(36): 1346-1351
Published online Dec 28, 2017. doi: 10.4254/wjh.v9.i36.1346

This study shows gender differences for the inpatient management of HCC. Women are still more likely to undergo resection which is consistent with prior publications. This study also determined that women are more likely to undergo ablation. Women may be more likely to undergo these procedures because of functional status, compensated disease, and increased likelihood of undergoing screening exams that allow them to be diagnosed earlier. Despite advances in treatment of HCC, females are more likely to receive curative treatment with resection and ablation.


Women receive more inpatient resections and ablations for hepatocellular carcinoma than men 
Lindsay Sobotka, Alice Hinton, Lanla Conteh

Introduction
The incidence of hepatocellular carcinoma (HCC) in the United States is increasing. In 2016, it is estimated that more than 35000 people in the United States will be diagnosed[1]. The diagnosis has tripled since the 1980s. Men are three times as likely to be diagnosed with HCC as women[2]. Once diagnosed with HCC, survival rates are dependent on the stage with a 5 year survival of approximately 30.5 and metastatic HCC survival of 3.1[2].

There has been an emphasis on evaluating gender disparities in healthcare; HCC is not an exception. Gender disparities in the treatment for HCC have been noted in the past, specifically in transplantation. Studies reveal that men were more likely to receive a liver transplantation during pre-Model for End Stage Liver Disease (MELD) organ allotment, while women were more likely to die while waiting for organ transplantation[3]. Other studies have concluded that women were more likely to receive resection for earlier stage disease[4].

The aim of this study is to use the Nationwide Inpatient Sample (NIS) to determine if gender disparities still exist in the inpatient treatment for HCC.

We hypothesize that gender disparities continue to exist and seek to identify potential factors associated with this disparity.

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