Wednesday, October 26, 2016

Review - Laboratory tests relevant for the treatment of HCV infection in the era of DAA therapy

Clinical Laboratory Testing in the Era of Directly Acting Antiviral Therapies for Hepatitis C

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Citation Wilson EM, Rosenthal ES, Kattakuzhy S, Tang L, Kottilil S. 2017. Clinical laboratory testing in the era of directly acting antiviral therapies for hepatitis C. Clin Microbiol Rev 30:23–42. https://doi.org/10.1128/CMR.00037-16.

SUMMARY
Directly acting antiviral (DAA) combination therapies for chronic hepatitis C virus (HCV) infection are highly effective, but treatment decisions remain complex. Laboratory testing is important to evaluate a range of viral, host, and pharmacological factors when considering HCV treatment, and patients must be monitored during and after therapy for safety and to assess the viral response. In this review, we discuss the laboratory tests relevant for the treatment of HCV infection in the era of DAA therapy, grouped according to viral and host factors.


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I highly suggest you follow Henry E. Chang on Twitter if you are interested in reading full text articles about the treatment and management of hepatitis C. A link to the above mentioned article (PDF) was tweeted by Mr. Chang this morning.

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