Sunday, January 28, 2018

Vitamin D deficiency and hepatitis viruses-associated liver diseases: A literature review

Also On This Blog
Tuesday, March 13, 2018
Higher levels of vitamin D is associated with a lower risk of liver cancer:
https://hepatitiscnewdrugs.blogspot.com/2018/03/higher-levels-of-vitamin-d-is.html

World J Gastroenterol. Jan 28, 2018; 24(4): 445-460
Published online Jan 28, 2018. doi: 10.3748/wjg.v24.i4.445

Review
Vitamin D deficiency and hepatitis viruses-associated liver diseases: A literature review 
Nghiem Xuan Hoan, Hoang Van Tong, Le Huu Song, Christian G Meyer, Thirumalaisamy P Velavan

Core tip: Vitamin D deficiency is common and associated with chronic liver diseases. Several studies have ascribed a strong association of vitamin D insufficiency with unfavorable clinical courses and progression of liver disease in hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. However, any causal relation is so far not fully understood. In addition, there are inconsistent results with regard to the impact of vitamin D supplementation on the virological response to IFN-based therapy; this applies particularly to HCV infections. The present review addresses general aspects of vitamin D deficiency and focuses on its association with HBV and HCV infection. Furthermore, the effects of vitamin D supplementation in combination with IFN-based therapy on the virological response in HBV and HCV infected patients are reviewed.

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