Review Article
August 25, 2016 | P.S. Ge and B.A. Runyon
N Engl J Med 2016;375:767-77. DOI: 10.1056/NEJMra1504367
This guide to the practical treatment of patients with cirrhosis summarizes recent developments. It includes advice on medical management, invasive procedures, nutrition, prevention, and strategies to protect the cirrhotic liver from harm.
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Epidemiology and Diagnosis
The major causes of cirrhosis include chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, alcoholism, and nonalcoholic steatohepatitis. HCV infection and nonalcoholic steatohepatitis are the causes that are primarily responsible for the growing burden of cirrhosis in health care. Owing to the increasing prevalence of nonalcoholic fatty liver disease, cirrhosis related to nonalcoholic steatohepatitis is predicted to surpass HCV-related cirrhosis as the most common indication for orthotopic liver transplantation in the United States. Chronic injuries to the liver are synergistic; it is not unusual to see patients with cirrhosis that is due to a combination of chronic viral hepatitis, obesity, and alcoholism.....
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Of Interest
New virtual patient case: decompensated cirrhosis
Case 5 - Decompensated Cirrhosis
In June "ViralEd" released "HCV Virtual Patient" an easy to follow video CME with a look at different case scenarios. This activity is a helpful starting point for people who failed treatment, have cirrhosis or want to learn more about current treatment options for various HCV genotypes. After each video module participants can either answer the questions, or click on Curbside Consult
Begin here....
Full Text - Download PDF
Epidemiology and Diagnosis
The major causes of cirrhosis include chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, alcoholism, and nonalcoholic steatohepatitis. HCV infection and nonalcoholic steatohepatitis are the causes that are primarily responsible for the growing burden of cirrhosis in health care. Owing to the increasing prevalence of nonalcoholic fatty liver disease, cirrhosis related to nonalcoholic steatohepatitis is predicted to surpass HCV-related cirrhosis as the most common indication for orthotopic liver transplantation in the United States. Chronic injuries to the liver are synergistic; it is not unusual to see patients with cirrhosis that is due to a combination of chronic viral hepatitis, obesity, and alcoholism.....
Continue reading....
Of Interest
New virtual patient case: decompensated cirrhosis
Case 5 - Decompensated Cirrhosis
In June "ViralEd" released "HCV Virtual Patient" an easy to follow video CME with a look at different case scenarios. This activity is a helpful starting point for people who failed treatment, have cirrhosis or want to learn more about current treatment options for various HCV genotypes. After each video module participants can either answer the questions, or click on Curbside Consult
Begin here....
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