Monday, October 19, 2015

Decentralized HCV Treatment is Effective!

Decentralized HCV Treatment is Effective!
Posted on October 18, 2015
The American Journal Of Medicine

Given the safety, tolerability, simplicity, and efficacy of hepatitis C direct-acting antiviral (DAA) regimens, decentralizing treatment from gastroenterologists and hepatologists to other specialists, community-based primary care physicians, or appropriately supervised mid-level providers (ie, task-shifting) may be an effective strategy to increase treatment rates, cure rates, and really start addressing to the HCV epidemic. The SVR-12 rates achieved by a US rural outreach program based on the task-shifting model—88 % overall, 86 % in genotype 1 patients, 94 % in genotype 2 patients, and 83 % in genotype 3 patients—are comparable to those achieved in phase II and III clinical trials utilizing these regimens. By utilizing task-shifting, wherein a local mid-level provider monitored patients on DAA treatment with indirect supervision of a specialist, high rates of treatment adherence and success in medically underserved areas was achieved.

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