Featuring HCV research, news and views
Just Published
We begin with the August print edition of "HCV Next" published today online at "Healio.""HCV Next" offers information on a range of topics, which include diagnosis, new combination therapies, side effects, drug/drug interaction, guidelines, fatty liver disease and more.
Table of Contents
5 QUESTIONS
A Conversation with Mitchell Shiffman, MD
IN THE JOURNALS
Study Suggests Less Than 1% of Acute HCV Cases Reported to the CDC
Study Shows low SVR Among Veterans on Sofosbuvir-Based Regimens
Study Shows Medicaid Restrictions for Sofosbuvir Create Barriers for Care
Alisporivir Plus Ribavirin Yields High Response Rates for HCV Genotype 3
Combination Regimen Yields High SVR in Former Injection Drug Users
FDA Showcases Clinical Trial Design, Regulation for HCV
Experts: Needle Exchange Programs Prevent Outbreaks Among IDUs
TREND WATCH
TURQUOISE-III: Treatment Yields 100% SVR12 for HCV Genotype 1b
California Could Spend Nearly $5 Billion on HCV Drugs Over Next Year
Newsletter
HCV Advocate Mid-Month Newsletter
Aug 15
In this month’s column of HCV Drugs I discuss the exciting news about the Food and Drug Administration (FDA) approval of AbbVie’s and BMS’s HCV medications, the study results from AbbVie’s once-a-day combination to treat genotype 1b, and the acceptance by the FDA of Merck’s new drug application for grazoprevir and elbasvir and the decision date.
HCV Advocate Fact Sheets
Genotype 3: Daklinza plus Sofosbuvir
Aug 15
In this month’s column of HCV Drugs I discuss the exciting news about the Food and Drug Administration (FDA) approval of AbbVie’s and BMS’s HCV medications, the study results from AbbVie’s once-a-day combination to treat genotype 1b, and the acceptance by the FDA of Merck’s new drug application for grazoprevir and elbasvir and the decision date.
HCV Advocate Fact Sheets
Genotype 3: Daklinza plus Sofosbuvir
Liver Night - On Your Health First
Latest News on Hepatitis C Cures
by DR. JOE GALATI on 08/16/2015
For tonight’s broadcast of Your Health First, Dr. Rashid Khan joins me to discuss the latest news on fatty liver disease, and the new therapies for hepatitis C, which results in a cure rate of over 95% of the cases.
Podcast At CMAJ
CMAJ Blogs
Podcast At HealthLink On Air
Blog Updates From Around The Web
Hepatitis C, Marijuana, and the Liver
CMAJ Blogs
CMAJ Blogs hosts the Medical Student Humanities Blog, as well as blogs by CMAJ editors and guest bloggers.
Social determinants of hepatitis C
Dr. Tyndall draws attention to the fact that although new treatments for hepatitis C virus are much more effective, we must not forget to address the social drivers of the disease, especially amongst people who inject drugs. IV drug users, both current and past, make up the majority in the second wave of HCV infection.
Source
Dr. Tyndall draws attention to the fact that although new treatments for hepatitis C virus are much more effective, we must not forget to address the social drivers of the disease, especially amongst people who inject drugs. IV drug users, both current and past, make up the majority in the second wave of HCV infection.
Source
Podcast At HealthLink On Air
How latest techniques help surgeons fight cancer, other diseases of liver, pancreas, gallbladder
by Jennifer Congel
Obesity and drug abuse can lead to fatty liver and hepatitis C, which are major factors for developing liver cancer, according to Ajay Jain, MD, associate chief of hepatobiliary and pancreatic surgery at Upstate. Jain, who specializes in cancer surgery, describes the latest procedures – often minimally invasive and robotically assisted — to treat cancers and other diseases of the liver, pancreas, gallbladder and bile ducts. He also reviews promising new research on early detection of pancreatic cancer.
Listen here...
by Jennifer Congel
Obesity and drug abuse can lead to fatty liver and hepatitis C, which are major factors for developing liver cancer, according to Ajay Jain, MD, associate chief of hepatobiliary and pancreatic surgery at Upstate. Jain, who specializes in cancer surgery, describes the latest procedures – often minimally invasive and robotically assisted — to treat cancers and other diseases of the liver, pancreas, gallbladder and bile ducts. He also reviews promising new research on early detection of pancreatic cancer.
Listen here...
Blog Updates From Around The Web
Hepatitis C, Marijuana, and the Liver
By Lucinda K. Porter, RN
Regular readers have probably figured out that my notions are liberal-leaning. I believe in medical coverage for everyone, including hepatitis C treatment for anyone who wants it. I advocate treatment for active drug users, prisoners, and people with no liver damage. I believe that health is a right, not a privilege. I also believe that spending our healthcare dollars is a wise investment in society and helps to increase productivity.
By Lucinda K. Porter, RN
A chronic hepatitis C diagnosis often spurs us to educate ourselves about the liver. Few of us think about our kidneys, but we should. People living with hepatitis C have a higher risk of developing kidney failure compared to those without hep C (52.6% vs. 38.4%).By Greg Jefferys
I have written previously of UK Doctors' fear of prescribing generic Hep C medicine (genericnophobia) and have recently had correspondence with a London GP and a Welsh patient consulting a liver specialist in Wales that sheds some light on the source of this strange psychological condition, genericnophobia, which affects more than 90% of British medical practitioners.
By Grace Campbell
Often we make a commitment to something and it all sounds very reasonable, until something unrelated, unexpected and unplanned blows it out of the water.
By Grace Campbell
Often we make a commitment to something and it all sounds very reasonable, until something unrelated, unexpected and unplanned blows it out of the water.
Karen Hoyt
What I really need to do is to hire a professional. But – that’s way out of my price range – for now… so I guess I’ll have to do.
HAVE GUN, WILL TRAVEL–JETGUNS
HAVE GUN, WILL TRAVEL–JETGUNS
Well, there you have the particulars. I suspect it is much more than plausible that the jetgun was capable of cross-contamination by any of the above even if no one had flinched and bled.
Pennsylvania’s Medicaid covers Sofosbuvir if the patient has an F3 or F4 stage of liver fibrosis and demonstrates a record of at least 6 months abstinence from drugs and alcohol.
**Ricki**
Every time I took my son in to the doctors, I would pretend that it was just a regular checkup, but I knew that eventually, his blood work would probably come back with an elevated liver panel.
My Integrative Strategies for Managing Hepatitis C
By George M. Carter
My Integrative Strategies for Managing Hepatitis C
By George M. Carter
My HCV genotype is 1A. For many years, it was considered harder to treat, with a lower likelihood of a sustained viral response (SVR) -- which is considered being cured -- when using alpha interferon or, even later, a combination of pegylated interferon and ribavirin. The low likelihood of success, the 48 weeks of injections and the horrific side effects persuaded me to wait. In addition, I was not too concerned since some data I saw suggested that not everyone with HCV goes on to develop cirrhosis.
Anthem sued for denying Hep C drug treatment
By Jason Schossler
From Westlaw Journal Insurance Coverage: Anthem Blue Cross Life & Health Insurance Co. is facing a proposed class-action lawsuit for allegedly refusing to cover the newly approved but expensive hepatitis C treatment Harvoni, which reportedly can cure most cases of the disease within eight to 12 weeks.
A Tale of Two Liver Transplants: Altruistic Compassion for a Compassionate Altruist
By Nathan Sheon
"Talk about your life changing in an instant,” Helen said, remembering her first diagnosis of acute liver failure. The doctor told her family there was nothing more to be done, and she was given two weeks to live.
Preparing for College, Dating and Disclosing Hepatitis B
Anthem sued for denying Hep C drug treatment
By Jason Schossler
From Westlaw Journal Insurance Coverage: Anthem Blue Cross Life & Health Insurance Co. is facing a proposed class-action lawsuit for allegedly refusing to cover the newly approved but expensive hepatitis C treatment Harvoni, which reportedly can cure most cases of the disease within eight to 12 weeks.
A Tale of Two Liver Transplants: Altruistic Compassion for a Compassionate Altruist
By Nathan Sheon
"Talk about your life changing in an instant,” Helen said, remembering her first diagnosis of acute liver failure. The doctor told her family there was nothing more to be done, and she was given two weeks to live.
Preparing for College, Dating and Disclosing Hepatitis B
When my daughter, who has chronic hepatitis B, packed for her freshman year of college, I peppered her with warnings about the need for standard precautions and condoms. I suggested wording for a future conversation where she would disclose her infection and negotiate safe sex with a potential partner.
Of Interest
Of Interest
Nature
Registered clinical trials make positive findings vanish
Chris Woolston
A study showing a fall in positive trial results after the roll-out of clinicaltrials.gov attracted much attention on social media.
Healthy You
Junk Food Disguised as Healthy: Don’t Be Fooled
Dr. Joe Galati
Good nutrition is a requirement for wellness. There is no doubt that good nutrition prevents disease. Most reasonable people seek out foods that are nutritions, and thus support wellness. But, you need to beware that the food marketers are taking advantage of you-big time.
Happy Sunday!
Tina
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