Thursday, June 20, 2013

Healio-SVR more dependent on adherence to treatment duration than dosing interval

Hepatitis A outbreak affects 118 people in eight states
June 20, 2013
As of June 18, a hepatitis A virus outbreak, potentially associated with a frozen food blend has infected 118 people across eight states, according to the FDA. Forty-seven percent of those infected have been hospitalized but no deaths have been reported. CDC has conducted interviews with 116 of the infected people and 93 recalled eating the blend.
Full Story »

Liver biopsy, mental health did not affect HCV treatment
June 20, 2013
Having a pretreatment liver biopsy did not predict whether patients completed a full treatment course for hepatitis C, researchers reported. In subsequent...More »

SVR after triple therapy maintained long-term durability in HCV patients
June 20, 2013
Nearly all patients with chronic hepatitis C who achieved sustained virologic response to therapy with pegylated interferon, ribavirin and direct-acting...More »

SVR more dependent on adherence to treatment duration than dosing interval
June 19, 2013
Patients with chronic hepatitis C genotype 1 had higher sustained virologic response rates with better treatment duration adherence, while adherence to...More »

High daily dose, lipophilicity indicate risk for drug-induced liver injury
June 18, 2013
A drug with a dose of 100 mg or greater and high lipophilicity is significantly more likely to lead to drug-induced liver injury, according to a recent...More »

Patients with HCV, occult HBV at greater risk for mortality, HCC, cirrhosis
June 17, 2013
Patients coinfected with chronic hepatitis C and occult hepatitis B were more likely to develop cirrhosis or hepatocellular carcinoma and had poorer...More »

No impact on acute rejection from interferon/ribavirin HCV therapy among renal transplant recipients
June 14, 2013
Chronic hepatitis C-infected renal transplant recipients receiving interferon-based therapy experienced modest efficacy rates but were not at elevated...More »

Meeting News CoverageVideo
Future HCV therapies will improve SVR rates, treatment durations, tolerability
June 13, 2013
ORLANDO, Fla. — Anna S. Lok, MD, professor of internal medicine at the University of Michigan in Ann Arbor, Mich., discusses upcoming advancements...More »

Deceased-donor partial liver transplants viable for young children
June 13, 2013
Outcomes of partial liver transplantation from deceased donors for very young recipients are comparable to those from whole liver transplantation,...More »

Interferon-based therapy benefited HCV/HIV coinfected patients despite viral relapse
June 12, 2013
Patients with HCV/HIV coinfection who experienced viral relapse after treatment with interferon-based therapy still experienced some clinical benefit,...More »

High HBV viral load tied to low serum vitamin D levels
June 11, 2013
Patients with chronic hepatitis B who also were vitamin D deficient had significantly higher HBV DNA levels than patients with adequate vitamin D...More »

David Thomas, MD, MPHCover Story
Interferon-free treatment for HCV may soon be a reality
Sofosbuvir (Gilead) plus ribavirin appears to be the most promising thus far.
More »

No comments:

Post a Comment