Friday, December 28, 2012

2012 - Latest advances in curing hepatitis C

Dr. Mitchell Shiffman, of the Liver Institute of Virginia, talks with Hepatology Digest at the American Association for the Study of Liver Diseases about the latest advances in curing hepatitis C, specifically about the role of peginterferon in the era of triple therapy for HCV.

Tens of thousands of New York’s most vulnerable patients enrolled in Medicaid managed care plans are being forced to use mail order pharmacies to fill their HCV specialty prescriptions. This policy is detrimental to the long term medical outcome for chronically ill marginalized patients living with hepatitis C (HCV).

Peg-Interferon Plus Ribavirin Safe and Effective in Children
Joe Barber Jr, PhD
Children and adolescents infected with hepatitis C virus (HCV) can be safely and effectively treated with peg-interferon (PEG-IFN) in combination with ribavirin (RBV), according to the findings of a meta-analysis and review.    

The CDC's recommendations were made because the agency estimated that between 45% and 85% of adults with chronic HCV do not know they are infected. HCV is often asymptomatic and without risk factors for screening, the infection could go undiagnosed until after the liver has sustained significant damage.

In summary, we demonstrate a novel relationship between HCV infection and IFN responsiveness using a well-defined HCV continuous culture system

Among patients with chronic hepatitis C virus (HCV) infection and advanced hepatic fibrosis, those who achieve a sustained virological response (SVR) to interferon-based therapy are much less likely to die from any cause, according to the findings of a multicenter, long-term follow-up study.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed the first synthetic compound that can reverse the effects of a serious metabolic condition known as fatty liver disease. True to its name, the disease involves an abnormal buildup of fat in the liver.
MicroRNAs are small RNA molecules that regulate the expression of various genes. In this issue of the Journal of Clinical Investigation, researchers led by Shelly Lu at the University of Southern California identified a...
As long as you are aware of how to proceed safely, having Hepatitis C does not need to hinder your sex life.
Armed with elderberry, those with Hepatitis C have a helpful tool to persevere through this cold and flu season.
Investment Commentary
Off Topic
Videos Highlight Behavior and Health
Behavior and social factors play key roles in illness and health. NIH has released new videos that highlight outstanding findings in behavioral and social science research.

“Understanding our behavior and making better decisions puts us in charge of our own health,” says Dr. Robert Kaplan, director of NIH’s Office of Behavioral and Social Sciences Research. “These short films highlight some of the benefits of behavioral and social science research—both for us as individuals and for society as a whole.”

The videos feature prominent scientists describing their work. They focus on mindless eating, risk-taking related to substance abuse, diabetes management and the evolution of skin pigmentation. The videos are available at and on the NIH YouTube channel at

“There are personal take-aways in each of these films, ”Kaplan says, “but they also demonstrate both the excitement and reward of behavioral and social science research. I hope every viewer learns something useful. And I hope we’re engaging the next generation of researchers to enter this dynamic and productive field.”

I want to discuss a patient of mine. He is a man in his 50s. He is not overweight, although he has a family history of type 2 diabetes. His body mass index is about 23, which is not bad. One caveat, though, is that his son, who was about 12 years old when I first saw the patient, has type 1 diabetes.

The first population study to compare the prevalence of diagnosed fibromyalgia (FM) to the general population prevalence of people reporting symptoms that met the updated 2010 American College of Rheumatology (ACR) diagnostic criteria indicates that FM may be more common than previously thought and that most FM cases are not being diagnosed, especially in men.

No comments:

Post a Comment