This blog is all about current FDA approved drugs to treat the hepatitis C virus (HCV) with a focus on treating HCV according to genotype, using information extracted from peer-reviewed journals, liver meetings/conferences, and interactive learning activities.
Risk Of Developing Liver Cancer After HCV Treatment
In this learning activity the good doctor will discuss screening strategies, stigma, patient-related barriers to treatment, hepatitis C testing for identifying current infection, and tests used to stage fibrosis. Also discussed is treatment for HCV patients with cirrhosis, as well as treatment adherence, duration, treatment according to HCV genotype, ending with "How Much Care Do The Cured Need?"
Although the learning activity is aimed at HCV specialists, this short patient-friendly presentation is beneficial for anyone considering HCV testing and treatment.
PeerView CME
Published on May 25, 2018
Released April 30, 2018
Ira M. Jacobson, MD, discusses hepatitis C virus in this CME/CE activity titled "HCV From Screening to Cure: A Closer Look at Changing At-Risk Populations and an Evolving Treatment Landscape." For the full presentation and infographics, complete CME/CE information, and to apply for credit, please visit us at http://www.peerview.com/FNC865. CME/CE credit will be available until April 29, 2019.
This CME/CE activity is jointly provided by Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education.
How To Watch - First in Human
Welcome to this issue of "Weekend Reading," if you missed the new Discovery documentary "First in Human" about cutting-edge research taking place at the "National Institutes of Health’s Clinical Center," watch past and current episodes on either your TV (if you have on demand) or a favorite device by logging into your TV provider (cable or satellite company); list provided further down this page.
Documentary Background
Narrated by Jim Parsons,"First in Human" is a look at real-life stories of patients, researchers, and physicians who participate in clinical trials at the National Institutes of Health’s Clinical Center. NIH Clinical Center is the Nation's largest hospital devoted to clinical research, medical research that is saving and improving lives, and laying the groundwork for drugs used to cure devastating diseases.
Start by reading about America's first government-run hospital: "NIH Clinical Center," or review additional information about the "program," and just for fun, watch Jim Parsons on "Jimmy Kimmel" explain why he took part in the documentary.
Hepatitis C The NIH Connection
In 1999, as a hepatitis C patient, I jumped into the pool of clinical trials, swimming around until I was completely cured. Rather you or a loved one have benefited from taking part in a clinical trial, or directly from medical research, we all have, know that you will be deeply moved by this awe inspiring documentary.
Did You Know?
In the mid-20th century across the United States, patients were contracting Hepatitis following blood transfusions. Researchers in the Clinical Center Blood Bank, led by Harvey Altar, developed lifesaving tests that screened for Hepatitis B in the blood supply and led to the virtual elimination of cases in which patients contracted Hepatitis B through blood transfusions. The same researchers working in the Clinical Center along with others working outside of NIH also eventually identified Hepatitis C and a test for screening for Hepatitis C in blood banks.....
History of NIH Clinical Center
First in Human: The Trials of Building 10
On July 6, 1953, the NIH Clinical Center welcomed its first patient, Charles Meredith, a Maryland farmer. Meredith arrived at the Clinical Center to participate in a study on hormone treatments for prostate cancer. His admission to the Clinical Center was the start of a unique research effort by the Federal government.....
First in Human is a three-part documentary capturing the real-life experiences of doctors, researchers, staff, patients and their caregivers, at the NIH Clinical Center.
The documentary airs on three sequential Thursday evenings on August 10, 17, and 24, at 9:00 p.m. ET/PT on Discovery.
For over a year, Discovery, in collaboration with John Hoffman (Weight of the Nation, Sleepless in America), was embedded in the NIH Clinical Center to capture the challenges faced in diagnosing and treating diseases.
Narrated by Jim Parsons (Big Bang Theory, Hidden Figures), the three-episode series showcases the innovative work that takes place within the NIH Clinical Center and provides an in-depth look at the reality of experimental medicine in clinical trials.
Watch Live Click on an episode (sign in key) and pick your provider.
Sign in with your TV provider to stream the program, here is a list of providers.
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On this lovely Super Bowl Sunday (I really only care about the halftime show with Katy Perry) we have two videos to share, both published by Dr. Galati over the weekend.
The first video is an overview of newly approved treatments; Sovaldi, Harvoni, Olysio, and Viekira Pak. The second video is a look at the importance of maintaining a diet low in sodium for people living with liver disease and cirrhosis. Stay connected by visiting Dr. Galati's Blog.
Joe Galati, M.D.
For those suffering from hepatitis C, there are new hepatitis C treatments with a very high cure rate. The new drugs include Sovaldi, Harvoni, Olysio, and Viekira Pak. These new HCV drugs have over a 90% cure rate. Treatment with these new hepatitis C therapies will vary based on the genotype, presence or absence of cirrhosis, and transplant status. Patients with HIV co-infection might also be treated.
Low Salt Diet in Cirrhosis and Liver Disease: Advise to Patients and Family
by Dr. Joe Galati on 02/01/2015
In those patients with liver disease and cirrhosis, maintaining a diet low in salt (also knows as sodium) can be difficult at times. With all the eating out that America does, this processed food is overloaded with salt and sodium. Thus, it is nearly impossible to maintain a diet low in sodium. Usually, the target goal is to consume less than 2,000 mg per day.
Links
Dr. Galati is an expert in liver disease, evaluating patients will all facets of liver disease, including hepatitis C, hepatitis B, cirrhosis, liver cancer, fatty liver disease, and liver transplantation.
Located in the Texas Medical Center, Dr. Galati and his team is seeing new patients for evaluation. for more information, visit www.texasliver.com.
Tune in every weekend for Your Health First, Dr. Galati's weekly radio program on Clear Channel's 740 KTRH. Program information can be found at www.yourhealthfirst.com. Each week, Dr. Galati and his experts discuss a wide range of health topics.
Houston's Morning News with Matt Patrick welcomes KTRH Medical expert Dr. Joe Galati, to discuss more about baby boomers who overall, need to be tested for Hep C. Some reports advise against it, but Dr. Galati defuses that by explaining why more baby-boomers have the Hepatitis C today, adding it's highly curable. Listen in for details.
Good morning everyone, today we have two videos offering basic information on hepatitis C and the liver. Topics range from transmission, testing, to new treatments.
Hepatitis C is a liver disease caused by the Hepatitis C virus, this video discusses screening, symptoms, treatments, and more about this curable disease.
For more free information on this and other digestive diseases and disorders the Society covers, please visit our website http://www.badgut.org/
Good day everyone, hope you all have a safe and enjoyable weekend. Tomorrow I begin a new chapter in my life, I'm moving across the state, only five minutes from my children and grandchildren. Here comes trouble!
I am so grateful to be healthy, after watching Kim Bossley share her story today on Second Opinion, I was reminded this morning of just how fortunate I am.
* I successfully treated HCV soon after being diagnosed in 2000
Summary Kim's Story and The Bonnie Morgan Foundation
Kim's story begins with her mother, Bonnie Morgan, who suffered with kidney disease since birth. Later in life when she needed a kidney transplant, Bonnie's mother Ruth proved to be a suitable match, the transplant was a success. Against all odds, three years after Bonnie's transplant, she gave birth to Kim, a mothers dream came true. Tragically, sometime later Bonnie found out both she and her child contracted hepatitis C through an earlier blood transfusion. The story continues, but should be read firsthand at The Bonnie Morgan Foundation, Co-Founded by Kim Morgan Bossley, in honor of her mother.
What Can We Learn from Recent Hepatitis C Treatments?
Published on Oct 2, 2014
On October 1, the Engelberg Center for Health Care Reform and the USC Schaeffer Center for Health Policy and Economics hosted a half-day forum to discuss the serious coverage challenges that accompany breakthrough treatments, such as the much-discussed new treatment for Hepatitis C, Sovaldi.
Dr. Kuemmerle along with Dr. Fasiha Kanwal discuss SVR rates using first generation DAA therapies, current agents, and what we can expect in the future. In addition, access to treatment is examined with an emphasis on making HCV treatment more affordable to everyone. Evolution of Hepatitis C Virus Treatment
An editorial in the August issue of CGH discusses changing treatment methods for Hepatitis C Virus infection over the last several years. Dr. Kuemmerle speaks to first author Dr. Fasiha Kanwal of Baylor College of Medicine.
Video Weekend: Understanding The Liver, and Cirrhosis
Good afternoon folks, welcome to our first edition of video weekend. Today's innovative videos offer a better understanding of HCV, how the liver works, possible disease complications, and a quick look at treatment, brought to you by Armando Hasudungan and Joe Galati, M.D.
Knowledge Is Power
The phrase “knowledge is power” is a profound one to be sure, especially when applied to hepatitis C. Acquiring knowledge about hepatitis C can lead to an early diagnosis, a cure, and important management strategies to treat complications of this sometimes life-threatening virus. For most people, this can be an enormous undertaking, one that is made easier through self-education, advocacy and loving support.
Hepatitis C is a serious disease, affecting almost 3 percent of the population worldwide, and up to 60-80 percent of those infected will go on to develop a chronic infection. In addition, more than 350,000 people die yearly from hepatitis C related diseases.
Disease Progression
The natural history of hepatitis C still remains controversial, research indicates that liver damage such as fibrosis or cirrhosis can take decades to develop. In an interesting article, found here, researchers named alcohol intake, co-infection with HBV or HIV, smoking, diabetes, obesity, age at time of infection, and duration of HCV infection, as several host factors relevant in determining the progression of hepatitis C. The latter two proved to be key factors associated with higher mortality risk. Links
To learn more about the basics of HCV click here, newly diagnosed click here, and finally for treatment information, click here.
Videos
Please take a few moments to view these engaging artful, and informative videos. Hopefully they will help you better understand the liver and various aspects of hepatitis C. Liver Anatomy and Blood Supply
The final official EASL press conference Hepatitis C - DAAs: continuing the advance towards a cure.
Published on Apr 12, 2014
Highlights data discussions on hepatitis C and progressions in treating genotype 4 and continuing towards a cure as well as Hepatocellular Carcinoma (HCC) and cirrhosis
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