About Fatty Liver, NAFLD, NASH & Cirrhosis
Start by learning more about Fatty Liver Disease, watch the following videos available online @ Fatty Liver Foundation.
Eating better tied to lower risk of liver disease
April 27, 2018
Start by learning more about Fatty Liver Disease, watch the following videos available online @ Fatty Liver Foundation.
Eating better tied to lower risk of liver disease
April 27, 2018
(Reuters Health) - People who make an effort to improve their diet may be more likely to have less fat in their livers and a lower risk of liver disease than individuals who stick to unhealthy eating habits, a U.S. study suggests.
Continue reading @ Reuters Health
Mediterranean diet reduces liver fat, risk for NAFLD
Ma J, et al. Gastroenterol. 2018;doi:10.1053/j.gastro.2018.03.038. March 30, 2018
Improved diet quality based on the Mediterranean-style diet score and Alternative Healthy Eating Index score correlated with less liver fat accumulation and a reduced risk for new-onset nonalcoholic fatty liver, according to a recently published study.
Continue reading @ Healio
NASH Education Program launches, initiates first international NASH day
March 29, 2018
The NASH Education Program, an independent legal entity and nonpartisan initiative designed to increase education and awareness of nonalcoholic steatohepatitis, recently launched in the U.S., according to a press release.
Continue reading @ Healio
Of Interest
Fatty liver is very common in hepatitis C virus (HCV) patients post-SVR
This particular study may be of interest to people with HCV, according to data published Mar 21, 2018 in the online journal World J Gastroenterology, evidence of steatosis was reported to be found in close to half of patients who achieve a sustained virologic response after treating with direct-acting antivirals.
Full-text, here....
Public Release: 30-Mar-2018
NASH Education Program launches, initiates first international NASH day
March 29, 2018
The NASH Education Program, an independent legal entity and nonpartisan initiative designed to increase education and awareness of nonalcoholic steatohepatitis, recently launched in the U.S., according to a press release.
Continue reading @ Healio
Of Interest
Fatty liver is very common in hepatitis C virus (HCV) patients post-SVR
This particular study may be of interest to people with HCV, according to data published Mar 21, 2018 in the online journal World J Gastroenterology, evidence of steatosis was reported to be found in close to half of patients who achieve a sustained virologic response after treating with direct-acting antivirals.
Full-text, here....
Public Release: 30-Mar-2018
Can a Mediterranean diet pattern slow aging?
The Gerontological Society of America
A series of six articles appearing in the March issue of The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences finds new correlations between a Mediterranean diet and healthy aging outcomes -- while also underscoring the need for careful approaches to the use of data in order to measure the diet's potential benefits.
A series of six articles appearing in the March issue of The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences finds new correlations between a Mediterranean diet and healthy aging outcomes -- while also underscoring the need for careful approaches to the use of data in order to measure the diet's potential benefits.
Among their findings, the new articles report on underlying mechanisms of the diet; the positive relationship between the diet and physical and cognitive function; the value of taking a coenzyme Q10 supplement while adhering to the diet; and the role of the diet in reducing inflammation. But in several of the studies, the level of benefit was dependent on how adherence to the diet was measured.
"Greater clarity on how this diet is defined, in both interventions and observational studies, will be critical in the aim of achieving a consensus on how to optimally apply this dietary pattern towards maximizing healthy aging," state Michelle A. Mendez, PhD, and Journals of Gerontology: Medical Sciences Editor-in-Chief Anne B. Newman, MD, FGSA, in an opening editorial.
Hallmarks of the Mediterranean diet include: a variety of minimally processed whole grains and legumes as the staple food; plenty of a huge diversity of fresh vegetables consumed on a daily basis; fresh fruits as the typical daily dessert; cold pressed extra-virgin olive oil, nuts, and seeds as the principal source of fat; moderate consumption of fish; dairy products consumed in low amounts; red and processed meat consumed in very low frequency and amounts; and wine consumed in low to moderate amounts only with meals.
There are a number of scales used to measure adherence to the diet. One of the journal's studies, conducted by researchers at the University of Paris 13, found that among test subjects, higher numbers on the Literature-based Adherence Score to the Mediterranean Diet were associated with higher odds of meeting certain healthy aging criteria. Similar results were found with another index, the Mediterranean Diet Score; however, use of the Mediterranean Diet Scale yielded a weaker correlation. In another study by researchers at the Autonomous University of Madrid, closer adherence to the diet was associated with a lower likelihood of physical function impairment in older adults, although in this case using the Mediterranean Diet Adherence Screener provided more significant results than the Mediterranean Diet Score.
The exact mechanism by which an increased adherence to the diet exerts its favorable effects is still unknown to scientists. However, writing in one of the new articles, researchers from Washington University in St. Louis state there is accumulating evidence of five important adaptations induced by the Mediterranean dietary pattern. These include lipid lowering; protection from oxidative stress and inflammation; modification of growth factors that can promote cancer; inhibition of nutrient sensing pathways by amino acid restriction and gut microbiota-mediated production of metabolites.
Editor's Choice - The Journals of Gerontology
Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms
Valeria Tosti, MD; Beatrice Bertozzi, PhD; Luigi Fontana, MD, PhD
Consuming a Mediterranean diet rich in minimally processed plant foods has been associated with a reduced risk of developing multiple chronic diseases and increased life expectancy. Data from several randomized clinic trials have demonstrated a beneficial effect in the primary and secondary prevention of cardiovascular disease, type 2 diabetes, atrial fibrillation, and breast cancer. The exact mechanism by which an increased adherence to the traditional Mediterranean diet exerts its favorable effects is not known. However, accumulating evidence indicates that the five most important adaptations induced by the Mediterranean dietary pattern are: (a) lipid-lowering effect, (b) protection against oxidative stress, inflammation and platelet aggregation, (c) modification of hormones and growth factors involved in the pathogenesis of cancer, (d) inhibition of nutrient sensing pathways by specific amino acid restriction, and (e) gut microbiota-mediated production of metabolites influencing metabolic health. More studies are needed to understand how single modifications of nutrients typical of the Mediterranean diet interact with energy intake, energy expenditure, and the microbiome in modulating the key mechanisms that promote cellular, tissue, and organ health during aging.
The Journals of Gerontology: Series A, Volume 73, Issue 3, 2 March 2018, Pages 318–326, https://doi.org/10.1093/gerona/glx227
View full text articleHealth Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms
Valeria Tosti, MD; Beatrice Bertozzi, PhD; Luigi Fontana, MD, PhD
Consuming a Mediterranean diet rich in minimally processed plant foods has been associated with a reduced risk of developing multiple chronic diseases and increased life expectancy. Data from several randomized clinic trials have demonstrated a beneficial effect in the primary and secondary prevention of cardiovascular disease, type 2 diabetes, atrial fibrillation, and breast cancer. The exact mechanism by which an increased adherence to the traditional Mediterranean diet exerts its favorable effects is not known. However, accumulating evidence indicates that the five most important adaptations induced by the Mediterranean dietary pattern are: (a) lipid-lowering effect, (b) protection against oxidative stress, inflammation and platelet aggregation, (c) modification of hormones and growth factors involved in the pathogenesis of cancer, (d) inhibition of nutrient sensing pathways by specific amino acid restriction, and (e) gut microbiota-mediated production of metabolites influencing metabolic health. More studies are needed to understand how single modifications of nutrients typical of the Mediterranean diet interact with energy intake, energy expenditure, and the microbiome in modulating the key mechanisms that promote cellular, tissue, and organ health during aging.
The Journals of Gerontology: Series A, Volume 73, Issue 3, 2 March 2018, Pages 318–326, https://doi.org/10.1093/gerona/glx227
View all articles: https://academic.oup.com/biomedgerontology/issue/73/3#583680-4917619
Recommended Reading
In January of this year, AASLD updated practice guidelines for the "Diagnosis and Management of NAFLD"
Fatty Liver Disease articles available on this blog:
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