In Case You Missed It - TAG Pipeline Report HIV, TB, and HCV
Treatment Action Group (TAG) is an independent, activist and community-based research and policy think tank fighting for better treatment, prevention, a vaccine, and a cure for HIV, tuberculosis, and hepatitis C virus.
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The 2017 Pipeline Report
Follow On Twitter
The 2017 Pipeline Report
July 2017
HIV, TB, and HCV
Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development
Written by Mike Frick, Annette Gaudino, Mark Harrington, Tim Horn, Richard Jefferys, Jeremiah Johnson, Erica Lessem, Marcus Low, and Lindsay McKenna
Hepatitis C
Annette Gaudino
AbbVie, Gilead, Merck, and Janssen have presented data at international congresses on efficacy across the six major genotypes; in difficult-to-treat populations, including patients with genotype 3 and cirrhosis; and patients with advanced kidney disease. Gilead also recently received approval for previously untreated adolescents, and presented data on ongoing clinical trials in young children. It would not be hyperbole to state that science has solved chronic HCV infection for all but individuals with decompensated cirrhosis—yet another powerful argument for early treatment. It must be noted that, as historically has been the case, all clinical trial data is based on majority male patient populations, with few people of color, particularly African Americans, taking part in clinical trials....
Updates On This Blog
Gilead's VoseviTM (Sofosbuvir/Velpatasvir/Voxilaprevir FDA Approved
On July 18, 2017 Gilead's VoseviTM (Sofosbuvir/Velpatasvir/Voxilaprevir) was FDA approved,
last month CHMP - the scientific committee of the European Medicines Agency adopted a positive opinion on the company’s marketing authorization application for Vosevi.
In this year's report:
July 2017
Introduction and Executive Summary
Mark Harrington
Mark Harrington
The Antiretroviral Pipeline
Tim Horn
Tim Horn
Preventive Technologies:
Antiretroviral and Vaccine Development
Jeremiah Johnson & Richard Jefferys
Antiretroviral and Vaccine Development
Jeremiah Johnson & Richard Jefferys
Research Toward a Cure and Immune-Based and Gene Therapies
Richard Jefferys
Richard Jefferys
The Tuberculosis Diagnostics Pipeline
Erica Lessem
Erica Lessem
The Tuberculosis Prevention Pipeline
Mike Frick
Mike Frick
The Tuberculosis Diagnostics and Treatment Pipeline for Children
Lindsay McKenna
Lindsay McKenna
HCV Pipeline: DAAs and Diagnostics in the Pangenotypic Era
Annette Gaudino
Annette Gaudino
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