Rarer HCV Types Still Need Attention

Rarer HCV Types Still Need Attention
Genotype 1 most common, but others also appear in U.S.

by Pippa Wysong
Contributing Writer, MedPage Today

Direct-acting agents (DAAs) have been so effective for genotype 1 that success rates have skyrocketed. Encouragingly, genotype 4 tends to also respond well to these agents. And, work continues on DAAs with newer antiviral agents showing excellent action on non-genotype 1 versions of HCV.....

When compared with other HCV patients, genotype 3 patients are relatively difficult to treat, especially those with cirrhosis. However, studies with sofosbuvir-velpatasvir are "encouraging, with SVR [sustained virologic response] rates of 97% in treatment-naïve patients and 90% in treatment-experienced patients."

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