Liver Cancer Rare After HCV Therapy
by Michael Smith Michael Smith
North American Correspondent, MedPage Today
North American Correspondent, MedPage Today
But some patients develop aggressive form of the disease
BOSTON -- For patients with advanced liver disease owing to hepatitis C (HCV), treatment with direct-acting antiviral agents did not increase the risk of hepatocellular carcinoma, a researcher said here.
The risk of liver cancer in the first year after such therapy was pretty much the same as it is in untreated patients, according to Alfredo Alberti, MD, of the University of Padua in Italy.
On the other hand, the rare patients who developed cancer after HCV treatment were more likely to have an aggressive form of the disease, Alberti told reporters at the American Association for the Study of Liver Diseases (AASLD) annual meeting.
The findings, from a large prospective cohort of patients in northern Italy, should help to settle what has been a "controversial and confusing issue," Alberti said, with small studies yielding conflicting results on the issue.
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