SVR after HCV therapy led to long-term clinical cure

SVR after HCV therapy led to long-term clinical cure
Hedenstierna M, et al. Aliment Pharmacol Ther. 2015;doi:10.1111/apt.13096
April 13, 2015

Achieving sustained virological response after treatment with pegylated interferon alpha-2b and ribavirin corresponded to a long-term cure for hepatitis C virus infection, according to study data.

“To better understand the clinical importance of residual HCV RNA after SVR, we screened 54 patients 5 [to] 20 years after SVR for HCV RNA traces in plasma, [peripheral blood mononuclear cells] and liver, and performed a full clinical and histological work-up,” the researchers wrote. “In addition, we evaluated humoral and cellular immune responses to HCV in these patients.”

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