Hepatitis C Virus Infection Increases the Risk of Alzheimer’s Diseases: A Population-Based Cohort Study in Taiwan

Of Interest - Herpes viruses associated with cognitive impairment   

Hepatitis C Virus Infection Increases the Risk of Alzheimer’s Diseases: A Population-Based Cohort Study in Taiwan

 

Wei-Che Chiu, MD, Pau-Chung Chen, MD,PhD
Institute of Occupational Medicine and Industrial Hygiene,
National Taiwan University Collage of Public Health, Taipei, Taiwan
Department of Psychiatry, Cathay General Hospital, Taipei, Taiwan

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Published online:7 DEC 2013 In European Journal of Neurology

 

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There were 2989 dementia cases from the HCV-infected cohort during the follow-up period of 533 861.1 person-years; the overall incidence rates of dementia differed from the non-HCV cohort (56.0 vs. 47.7 cases per 10 000 person-years, P < 0.05). The adjusted HR for dementia was 1.36 (95% CI 1.27–1.42) for HCV-infected patients after adjusting for alcohol-related disease, liver cirrhosis, hepatic encephalopathy and hepatocellular carcinoma.

 

http://www.ispor.org/awards/15euro/PIN79-presentation.pdf