This blog is all about current FDA approved drugs to treat the hepatitis C virus (HCV) with a focus on treating HCV according to genotype, using information extracted from peer-reviewed journals, liver meetings/conferences, and interactive learning activities.
Risk Of Developing Liver Cancer After HCV Treatment
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Wednesday, October 31, 2012
Hepatitis c clinical trials for October 2012-ClinicalTrials.gov
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ClinicalTrials.gov: hepatitis c | "Hepatitis C Virus" | updated in the last 30 days
Month Of October 2012
A Study of the Combination Regimen MK-5172, MK-8742, and Ribavirin in Participants With Chronic Hepatitis C (MK-5172-035)
Friday, October 26, 2012, 9:00:00 AM
Condition: Hepatitis C
Interventions: Drug: MK-5172; Drug: MK-8742; Drug: Placebo; Drug: Ribavirin
Sponsors: Merck; Merck
Not yet recruiting - verified October 2012
A Study to Evaluate Chronic Hepatitis C Infection in Treatment Experienced Adults
Thursday, October 25, 2012, 9:00:00 AM
Condition: Chronic Hepatitis C Infection
Interventions: Drug: ABT-450/r/ABT-267; Drug: ABT-333; Drug: ribavirin (RBV)
Sponsors: Abbott; Abbott
Not yet recruiting - verified October 2012
A Study of Different Durations of Treatment With MK-5172 in Combination With Ribavirin in Participants With Chronic Hepatitis C (MK-5172-039)
Thursday, October 25, 2012, 9:00:00 AM
Condition: Hepatitis C
Interventions: Drug: MK-5172; Drug: Ribavirin
Sponsors: Merck; Merck
Not yet recruiting - verified October 2012
A Study to Evaluate Chronic Hepatitis C Infection
Thursday, October 18, 2012, 9:00:00 AM
Condition: Chronic Hepatitis C Infection
Interventions: Drug: ABT/450/r/ABT-267; Drug: ABT-333; Drug: Ribavirin (RBV); Drug: Placebo for ABT-450/r/ABT-267; Drug: Placebo for ABT- 333; Drug: Placebo for Ribavirin (RBV)
Sponsors: Abbott; Abbott
Not yet recruiting - verified October 2012
A Study of Different Doses of MK-5172 Given With Pegylated Interferon Alfa-2b and Ribavirin to Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-038)
Wednesday, October 17, 2012, 9:00:00 AM
Condition: Chronic Hepatitis C (CHC)
Interventions: Drug: MK-5172; Biological: PegIFN-2b; Drug: Ribavirin; Drug: Placebo
ponsors: Merck; Merck
Not yet recruiting - verified October 2012
Sofosbuvir Plus Ribavirin Administered for Either 12 or 24 Weeks in Treatment-Naïve and Treatment-Experienced Egyptian Adults With Chronic Genotype 4 Hepatitis C Virus (HCV) Infection
Wednesday, October 17, 2012, 9:00:00 AM
Condition: Hepatitis C Virus
Interventions: Drug: Sofosbuvir; Drug: Ribavirin (RBV)
Sponsors: Gilead Sciences; Gilead Sciences
Recruiting - verified October 2012
Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction
Tuesday, October 16, 2012, 9:00:00 AM
Conditions: Chronic Hepatitis B Virus Infection; Chronic Hepatitis C Virus Infection
Intervention: Biological: BMS-914143 (Peginterferon Lambda-1a)
Sponsors: Bristol-Myers Squibb; Bristol-Myers Squibb
Recruiting - verified October 2012
A Study to Assess the Absolute Bioavailability and Pharmacokinetics of Simeprevir (TMC435) Administered as Single Oral Doses of TMC435 and an Intravenous Microdose of [3H]-TMC435 in Healthy Male Patients
Friday, October 12, 2012, 9:00:00 AM
Condition: Healthy Male Participants
Intervention: Drug: Simeprevir (TMC435)
Sponsors: Janssen R&D Ireland; Janssen R&D Ireland
Recruiting - verified October 2012
Viral Kinetics in HCV Clearance in Subjects With Hemophilia
Friday, October 05, 2012, 9:00:00 AM
Condition: Hepatitis C With Hemophilia
Interventions: Drug: Arm 1 - PegInterferon + Ribavirin (4 weeks); PegInterferon + Ribavirin + Telaprevir (12 weeks); PegInterferon + Ribavirin (8 weeks); Drug: Arm 2 - No 4-week lead in therapy; PegInterferon + Ribavirin + Telaprevir (12 weeks); PegInterferon+ Ribavirin (12 weeks)
Sponsors: University of Cincinnati; Kenneth Sherman; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified October 2012
Evaluation of Safety Tolerability and Antiviral Activity of ACH-0143102 Plus RBV Treatment Naive HCV GT1b Subjects
Tuesday, October 02, 2012, 9:00:00 AM
Condition: Chronic Hepatitis C Infection
Interventions: Drug: ACH-0143102; Drug: Ribavirin
Sponsors: Achillion Pharmaceuticals; Achillion Pharmaceuticals
Recruiting - verified October 2012
Safety and Efficacy of Sofosbuvir/GS-5885 Fixed-Dose Combination (FDC) +/-Ribavirin for the Treatment of HCV
Tuesday, October 02, 2012, 9:00:00 AM
Condition: Chronic Hepatitis C Virus
Interventions: Drug: Sofosbuvir/GS-5885 400/90 mg; Drug: Ribavirin
Sponsors: Gilead Sciences; Gilead Sciences
Recruiting - verified October 2012
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