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Friday, May 25, 2012

2012 - Update on the Diagnosis and Treatment of Hepatitis C

Clinical Reviews

Gastroenterology & Endoscopy News
ISSUE: MAY 2012 | VOLUME: 63:5

Update on the Diagnosis and Treatment of Hepatitis C

by Arun B. Jesudian, MD and Ira M. Jacobson, MD

Hepatitis C virus (HCV) infection is a national and global public health concern, affecting up to 4 million individuals in the United States and 200 million individuals worldwide. Despite a declining incidence of new HCV infections in the United States, the prevalence of advanced liver disease secondary to chronic HCV infection, including cirrhosis and hepatocellular carcinoma, is expected to rise in the coming years.

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 Update on the Diagnosis and Treatment of Hepatitis C

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Posted by HCV New Drugs at Friday, May 25, 2012
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Latest Update Feb 12, 2019 
Lancet Study: 
Direct-acting antivirals reduce risk of premature mortality and liver cancer for people with chronic hepatitis C 
These findings firmly counter those of a Cochrane review of direct-acting antiviral treatment trials that could neither confirm nor reject if direct-acting antivirals had an effect on long-term HCV-related morbidity and mortality. They also provide the best evidence to date to support guidance documents that recommend direct-acting antiviral treatment for all patients with chronic HCV infection.

The Controversy 
Rebuttal over Cochrane Review of DAAs 
A systematic review published by the Cochrane Collaboration suggested achieving SVR (cure) for patients using hepatitis C direct-acting antivirals (DAAs) doesn't correlate with any long term benefits. View each rebuttal and all ongoing media coverage.

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