Human genome: The first synthetic species

Steve Kroft profiles famous microbiologist J. Craig Venter, whose scientists have already mapped the human genome and created what he calls "the first synthetic species."

J. Craig Venter: Designing Life

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November 21, 2010 5:02

http://www.cbsnews.com/video/watch/?id=7076435n

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Hepatitis C

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Duke Institute for Genome
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The Center for Human Genome Variation (CHGV) was formed in 2005 as a Center within the Duke Institute for Genome Sciences & Policy, and in February 2010 was named an independent Center under the Duke University School of Medicine. Under the direction of Dr. David Goldstein, the CHGV is undertaking bold projects, with cutting-edge technologies, and a vibrant team of researchers with the goal of changing how genetics informs patient care

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Current Projects
1. We plan to follow-up the success of the previous findings and investigate the functional mechanism underlying the observed genetic associations.
2. We also plan to extend our research to patients infected with various strains of Hepatitis C and patients being treated with novel drug regimes under development.

Additional Publications
Thomas et al.

Genetic variation in IL28 and spontaneous clearance of hepatitis C.

Nature, 2009 Oct8;461(7265)798-801.
Thompson et al.

IL28B polymorphism improves viral kinetics and is the strongest pre treatment predictor of SVR in HCV-1 patients,

Gastroenterology, 2010.
Rallón et al.

Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus coinfected patients,

AIDS, 2010.Researchers discover areas in human genome that may help find causes of certain disorders

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From: HIV and Hepatitis
Do IL28B Gene Variations Affect Liver Disease Progression in People with Hepatitis C?

IL28B Gene Patterns and Liver Transplant Outcomes in Hepatitis C Patients

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Links Of Interest

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Researchers discover areas in human genome that may help find causes of certain disorders
By Thomas H. Maugh II

Nov. 4, 2010 Only 10 years after scientists laboriously unraveled the first sequence of a human genome, an international team said Wednesday they have sequenced the bulk of the genomes from more than 800 people in the pilot stage of the so-called 1000 Genomes Project that aims to complete 2,500 sequences by the end of 2012 at a cost of $120 million.

From Bioportfolio Role Of Genetics In Human Life Search

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