Tuesday, February 21, 2017

What are the Most Accurate Non-invasive Techniques for Measuring Liver Fibrosis and Steatosis?

What are the Most Accurate Non-invasive Techniques for Measuring Liver Fibrosis and Steatosis?

Magnetic resonance elastography (MRE) is more accurate than transient elastography (TE) in identifying liver fibrosis of stage 1 or more, researchers report in the February issue of Gastroenterology, using biopsy analysis as the standard. They also show that MRI-based proton density fat fraction (MRI-PDFF) analysis is more accurate than TE-based controlled attenuation parameter (CAP) assessment in detecting all grades of steatosis in patients with non-alcoholic fatty liver disease (NAFLD).

It is important to accurately measure the level of fibrosis in livers of patients with NAFLD, as it associates with long-term outcomes. Steatosis quantification is also important. Nonalcoholic steatohepatitis (NASH) is a strong indicator of disease progression, but until recently, only liver biopsies have been sufficient to identify inflammation.
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