Francesco Paolo Russo, Savino Bruno, Fabio Farinati
Digestive and Liver Disease
Data on the long-term outcome after antiviral therapy with Peg-Interferon and Ribavirin in patients with hepatitis C infection (HCV) and cirrhosis, who are at increased risk of developing liver decompensation (LD), hepatocellular carcinoma (HCC) and liver related death, showed that HCV eradication reduces both liver-related and non-liver-related mortality , thus leading to a life-expectancy similar to that of the general population . The clinical benefit of HCV eradication is more significant in patients with compensated cirrhosis and without clinically significant portal hypertension (PH) who do not develop LD and rarely HCC .
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Updated February 2017
Liver Cancer After Treatment For Hepatitis C
Research demonstrates that while SVR markedly reduced liver-related complications and liver cancer, some long-term risk for liver cancer remained in those who were cured of Hepatitis C. But after direct-acting antiviral therapy does the risk of developing liver cancer increase?