February 2017 Volume 43, Issue 1, Pages 123–132
Hepatitis C Virus Infection and Rheumatic Diseases
The Impact of Direct-Acting Antiviral Agents
Patrice Cacoub MD, Cloé Commarmond MD, David Sadoun MD, PhD, Anne Claire Desbois MD
KEY POINTS
Hepatitis C virus infection is associated with many extrahepatic manifestations, including rheumatic disorders such as arthralgia, myalgia, cryoglobulinemia vasculitis, and sicca syndrome.
The treatment of hepatitis C virus infection has long been based on interferon alfa, which was contraindicated in many autoimmune/inflammatory disorders.
The emergence of new oral interferon-free combinations now offers an opportunity for patients infected with hepatitis C virus with extrahepatic manifestations, including autoimmune/inflammatory disorders, to be cured with a short treatment duration and a low risk of side effects
Full Text
The Impact of Direct-Acting Antiviral Agents
Patrice Cacoub MD, Cloé Commarmond MD, David Sadoun MD, PhD, Anne Claire Desbois MD
KEY POINTS
Hepatitis C virus infection is associated with many extrahepatic manifestations, including rheumatic disorders such as arthralgia, myalgia, cryoglobulinemia vasculitis, and sicca syndrome.
The treatment of hepatitis C virus infection has long been based on interferon alfa, which was contraindicated in many autoimmune/inflammatory disorders.
The emergence of new oral interferon-free combinations now offers an opportunity for patients infected with hepatitis C virus with extrahepatic manifestations, including autoimmune/inflammatory disorders, to be cured with a short treatment duration and a low risk of side effects
Full Text
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