In Portsmouth, Ohio parents are engaged in a war void of any sustanial ammunition needed to combat the enemy. OxyContin continues to hold their children hostage in some cases even taking the lives of young and impressionable adolescents. The epidemic is so severe that located in the communities downtown store window is a memorial to those people who have died from prescription drug overdoses. The town is overcome with IV drug use with the cases of hepatitis C reaching new heights. Prescription drug use has become a national crisis, according to a 2010 released White House study detailing that substance abuse treatment admissions for prescription pain relievers increased by 400 percent between 1998 and 2008.
MIAMI, Feb. 28 (UPI) -- A U.S. Army veteran who turned up positive for HIV following a colonoscopy has filed a $20 million suit against the Veterans Administration.
Patients with HIV whose antiretroviral therapy was managed by nurses at regional clinics in South Africa did just as well as those whose care was handled by physicians at larger hospitals, researchers reported here.
By: MARY ANN MOON, Internal Medicine News Digital Network02/24/11A sustained virologic response to antiviral therapy signals a favorable prognosis in patients with decompensated cirrhosis due to chronic hepatitis C, reported Dr. Angelo Iacobellis and his colleagues in the March issue of Clinical Gastroenterology and Hepatology.
The Bristol-Myers Squibb Foundation has awarded four new grants to help improve awareness, prevention and care of hepatitis B (HBV) and hepatitis C (HCV) in China and India. The grants total nearly $1 million USD and bring...
Big Pharma; Johnson & Johnson
Vertex and partner Johnson & Johnson= Telaprevir
Johnson & Johnson=TMC435
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Outsourced; Extra Strength Tylenol Rapid Relief Gels
In 2009/2011 Recalled because of safety concerns; Johnson & Johnson’s Children’s Tylenol, Tylenol Arthritis Pain Caplets, Extra Strength Tylenol Rapid Relief Gels. The latter was traced to a fungicide that originated from a Puerto Rican plant.
Food and Drug Administration Commissioner Margaret Hamburg, M. D., said in July 2011, according to The Buffalo News.“Up to 40 percent of the drugs Americans take are imported, and up to 80 percent of the active pharmaceutical ingredients in those drugs come from foreign sources,”
The lawsuit was filed by Scott Bartz, a New Jersey resident who worked as a sales compensation manager from 1999 until 2007, when he alleges he was terminated in retaliation for repeatedly complaining about illegal marketing practices. His lawsuit also names the Omnicare nursing home operator and McKesson, the pharmaceutical wholesaler.
Here’s a lesson for a board of directors: never let a few setbacks deter you from giving your chief executive a raise, however modest. Consider Johnson & Johnson ceo Bill Weldon. Despite a breathtaking number of recalls spanning nearly every corner of the health care behemoth - over-the-counter meds, contact lenses, syringes, hip replacement devices - he received a 3 percent pay hike. His new base salary is $1.92 million, up from $1.86 million, according to a filing with the US Securities and Exchange Commission.
The health care giant just can’t seem to do anything right. On top of all the quality-control problems that have led to tens of millions of product recalls for over-the-counter meds, syringes, contact lenses and hip replacement devices, now Johnson & Johnson is recalling more than 660,000 Sudafed packages because the labeling has an extra ‘not’ in the instructions. Really.
Two years ago, Pfizer trumpted a deal in which Aurobindo, a large supplier of active pharmaceutical ingredients that is based in India, would make a few dozen generic meds for the brand-name drugmaker. The move was part of a grand plan to expand into generics with lower manufacturing costs and revive growth as patents on big-selling, brand-name meds began expiring.
Taking too many dietary supplements Very little convincing evidence exists that shows supplements are important to slow or prevent illness, said Dr. Ann Zerr, Indiana University School of Medicine physician specializing in women's health. Calcium and vitamin D are exceptions, and omega-3 fish oil supplements may be worthwhile, she added. If you don't focus on fruits and vegetables and whole grains in your diet, then a multivitamin is probably a good idea, Zerr said. But taking other vitamin pills is expensive and unnecessary - and those that are fat-soluble can be harmful.
One alcoholic drink a day seems to be beneficial for the heart and for diabetes prevention, Zerr said. Women have less muscle mass than men, so their ability to metabolize alcohol is different, and they can't safely handle as much.
"I see a lot of professional women drink more than one alcoholic drink a day," she said. "More than one seems to increase the risk of head and neck cancers and liver irritation."
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Drinks Companies Spread Liver Disease as Surely as Mosquitoes Do Malaria Opinion Anna Gilmore, professor of public health at the University of Bath and the UK Centre for Tobacco Control Studies, and a Health Foundation clinician scientist; and Jeff Collin, director of the Global Public Health Unit at Edinburgh University (The Guardian, London, online, February 21, 2011)"While the government sees food and alcohol companies as partners in health policy, public health increasingly recognises them as vectors of disease. The vector concept, adapted from infectious disease control, is simple: liver disease and myriad other health and social problems are being spread by alcohol companies just as the mosquito vector spreads malaria. The conduct of these corporate vectors should therefore be studied and where necessary countered."
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Complementary Medicine / Alternative Medicine News
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Do Home Remedies for Hepatitis C Work? February 28, 2011 Determining if home remedies for Hepatitis C actually work depends on which remedies are being used and what the treatment goal is. .
In its RESPOND-2 study, Merck defines a null responding patient — someone who is faring the worst under the current standard of care — as a patient whose viral load decreased less than 1 log after four weeks of standard treatment. That's a considerably different criteria from the US Food and Drug Administration, which defines null responders as 'less than a 2 log10 reduction in HCV RNA at week 12'.
Vertex used the FDA's definition of null responder in its study, REALIZE. Since both companies are trying to show that their protease inhibitor works better for patients for whom current options have failed, there is a remote chance that Merck's numbers might paint an artificially rosier picture."The original article from In Vito ; Notes from AASLD: Apples and Oranges and Null Responders
"Heart bypass patients may soon be able to get new arteries without having to sacrifice vessels from other parts of their body, thanks to ready-made, off-the-shelf artificial blood vessels…Artificial vessels could also be useful for people on kidney dialysis machines…There is plenty of testing left to do, in terms of safety and effectiveness of the transplants."
Question What's the big deal about accepting gifts from drug companies, especially if they are small? Does the medical profession's code of conduct apply to medical students?
Response from Sarah Averill, MD Resident, St. Joseph's Hospital and SUNY Upstate Medical University, Syracuse, New York
When a new pain medication came out last year, the staff in the office where I was rotating discussed how many prescriptions they were writing for that drug and how much they liked the fruit smoothies and gelato that the drug company representatives were bringing. "I don't like gelato," one secretary quipped. "More for us," laughed the physician assistants. It was weird for me to overhear their conversation, and it made me wonder, did a fruit smoothie actually motivate them to write those prescriptions?
Indeed, evidence suggests that gifts do influence prescribing habits. An article in JAMA, Physicians and the Pharmaceutical Industry: Is a Gift Ever Just a Gift?, illustrates the ways in which gifts appear to influence prescribing.[1] A recent radio broadcast, How to Win Doctors and Influence Prescriptions,[2] documented how the pharmaceutical industry promotes their products. Even under new rules, there is strong evidence that the pharmaceutical industry takes a sophisticated approach to "educating" physicians and their staff....
Question: What does silver mining have to do with selling plane and hotel tickets online? What do either of these activities have in common with the treatment of hepatitis C? Answer: Companies behind these endeavors boast some of the hottest stocks on the market today. Over the past year, priceline's share price has doubled, while shares of InterMune and Silver Wheaton have both gained roughly 170%.
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In Closing
Members of the Peer Education Project in Fife talking about the impact it has had on their life and dealing with Hepatitis C. The project is run by the Hepatitis C Resource centre - http://www.hepccentre.org.uk/
DDW 2012 Clinicians, researchers and scientists from around the world will gather for Digestive Disease Week® (DDW) 2012, the largest and most prestigious gastroenterology meeting, from May 19-22, 2012, at the San Diego Convention Center, CA. DDW, the annual meeting of the American Gastroenterological Association (AGA) Institute, is jointly sponsored by the American Association for the Study of Liver Diseases, the AGA, the American Society for Gastrointestinal Endoscopy and the Society for Surgery of the Alimentary Tract. Click here for updates
May 18-2012 U.S. health officials want all baby boomers to get tested for hepatitis C. The Centers for Disease Control and Prevention on Friday released draft recommendations calling for all baby boomers to get a one-time blood test for the liver disease. That's everyone born from 1945 to 1965. CDC - Draft Recommendations
Find Hepatitis Testing Year Round Near You Locate organizations offering Hepatitis testing and additional services vaccines and treatment in the NPIN Organizations Database.
A special supplementary issue of Gastroenterology with full text viral hepatitis review articles and commentaries available through open access. Click here to view an index of articles.
A Few Topics Include; Maximizing Opportunities and Avoiding Mistakes in Triple Therapy for Hepatitis C Virus
Will Interferon-Free Regimens Prevail?
Books Free from Hepatitis C About the Author Lucinda K. Porter, RN is an active hepatitis C advocate who writes, teaches, and lectures on the topic. She is recognized as a leader in her field based upon her professional experience and her first hand knowledge of living with the disease.
Ms. Porter has been a research nurse at Stanford University Medical Center specializing in HCV and her articles and guides have appeared in numerous HCV newsletters and journals.
Today, in addition to being a highly sought-after speaker, she continues to work with various HCV groups on behalf of patients and their families
Alisporivir-Three cases of acute pancreatitis, one fatal, have led the FDA to put a clinical hold on a trial of an investigational oral drug for hepatitis C called alisporivir, according to the product's manufacturer.
Projects In Knowledge Offered at the site is a program series of HCV Video Case Vignettes.In the videos individual patient case studies are discussed, topics include side effects, drug-drug interactions, treatment duration, and outcome.
AASLD - Liver Learning If you haven't yet explored the "Liver Learning" section available @ the AASLD web site you're missing out on the November meeting webcasts, video podcasts, abstracts and more.
2012 March 2012-New Antiviral Agents for Hepatitis C This article describes the direct acting antivirals and host-targeted agents that have recently been approved or have been tested in HCV-infected patients and discusses their two current paths of clinical development: with or without interferon-α.
Protease inhibitors: Silver bullets for chronic hepatitis C infection? Recent trials evaluated the safety and efficacy of two protease inhibitors, boceprevir (Victrelis) and telaprevir (Incivek), added to standard care with pegylated interferon and ribavirin, in patients with chronic hepatitis C virus (HCV) infection. These drugs open the door for triple therapy and other new therapies involving combinations of other direct-acting antiviral agents to become the new standard of care for this population.
Treatment of chronic hepatitis C genotype 1 with triple therapy comprising telaprevir or boceprevir A significant increase in the number of patients with CHC to be treated is expected for 2012, with triple therapy regimens that are more complex. These expected developments represent a significant challenge and will stretch current resources. The present Swiss Association for the Study of the Liver (SASL) expert opinion statement is not intended as guideline but shall provide some guidance on the management of CHC genotype 1 and the use of TPV and BOC
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Clinical Trials-
To learn more about Hepatitis C virus clinical trials or to find out if a study is enrolling patients in your area, please click here.
Hepatitis C-New Protease Inhibitor (NS3/4A) Drug Resistance Test LabCorp has begun offering nationwide its hepatitis C GenoSure NS3/4A assay, which is designed to identify NS3 and NS4A mutations and NS3-associated resistance to a pair of recently approved HCV protease inhibitors.
Multimedia-Videos and Podcasts
Can't Find What You're Looking For? Click On A Topic Below
SUPPORT A new national toll-free helpline has been launched for people affected by hepatitis C: 877-HELP-4-HEP (877-435-7443).
This new consumer-run helpline is staffed by specially trained peer counselors Monday through Friday, 9am to 7pm EST to provide emotional support, health information, and referrals.
HELP-4-HEP is a partnership among several well-known and nationally recognized nonprofits with a combined 90+ years’ experience in hepatitis C education, support and patient advocacy.
Click here to order a FREE Home Access Hepatitis C Test Kit
How Soon Should I Get Tested After Exposure ?
After the exposure (especially if the blood exposure involved another person known to have the hepatitis C virus), it is recommended that testing for the hepatitis C antibody be performed at 4 to 6 months after the exposure OR that testing for the hepatitis C virus itself (a test often called an HCV PCR or hepatitis C viral load test) be performed 4 to 6 weeks after the potential exposure. These tests are done to determine whether or not hepatitis C infection has occurred as a result of the exposure.;
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If this site contains copyrighted material the use of which has not been specifically authorized by the copyright owner, it is being made available in an effort to advance the understanding of the ethics dealing with medical practice, medical care, new drug research, drug trials, science and scientific research, human rights, social justice and, in addition, the law and politics which cover these areas. It is believed that this use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed to visitors of this “HCV New Drugs Blog” without profit to the blog or to those who by visiting this blog have expressed interest in receiving the included information for research and educational purposes. The material in this site is provided for educational and informational purposes only, and is not intended to be a substitute for a health care provider's consultation. Please consult your own appropriate health care provider about the applicability of any opinions or recommendations with respect to your own symptoms or medical conditions. The information on this site does not constitute legal or technical advice
Keeping current on the potential arrival of new, improved Hepatitis C drugs is a regular research venture for many who are living with the Hepatitis C virus.
I was 43, a mother of three when I found out I had HCV. I went on to be treated successfully in 2000.(Intron A/Riba).
Only people who have experienced a chronic illness understand the fear and apprehension felt with each step up the ladder, climbing closer to either medical treatment or a possible cure. These millions of people (I was one of them) who are living with chronic hepatitis C or just newly diagnosed are often left out in the cold, alone, with many unanswered questions. Enter the sleepless nights, anxiety, waking each day wondering what to do next.
My blog is here to help you learn about HCV, the new drugs to treat this disease along with news and updates.
Wishing you all a safe journey.
Tina
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